Louisville 79, N.C. A&T 48
Russ Smith scored 23 points and set a Louisville NCAA tournament record with a career-high eight steals, and Peyton Siva had eight assists as the Cardinals demolished North Carolina A&T in Lexington, Ky.
Louisville finished with a season-high 20 steals as it forced the Aggies (20-17) into 27 turnovers. It was the 11th straight win for the Cardinals (30-5).
Colorado St. 84, Missouri 72
Dorian Green scored 17 of his 26 points in the first half and eighth-seeded Colorado State used good shooting to run away from Missouri in Lexington, Ky.
Green, who went scoreless with five turnovers in last year's second-round upset to Murray State, did much better this time as the Rams shot nearly 58 percent in the first half.
Phil Pressey's 20 points led the Tigers (23-11).
Michigan State 65, Valparaiso 54
Derrick Nix had 23 points and a career-high 15 rebounds to help power third-seeded Michigan State past the 14th-seeded Crusaders in the Midwest Regional in Auburn Hills, Mich.
The Spartans went on a 26-5 run in the first half to take control, and cruised to an easy win.
Saint Louis 64, New Mexico State 44
Dwayne Evans scored 24 points, Cody Ellis added 12 points and fourth-seeded Saint Louis overwhelmed New Mexico State in San Jose, Calif.
Playing through the death of Rick Majerus in December, Saint Louis reached another mark for its late coach. The Billikens (28-6) eclipsed the 1988-89 team's school record of 27 victories.